Biothera Research Papers

Articles on Biothera compounds that were published in peer-reviewed science and medical journals:


February 2008

Yeast-Derived β-Glucan Augments the Therapeutic Efficacy Mediated by Anti-Vascular Endothelial Growth Factor Monoclonal Antibody in Human Carcinoma Xenograft Models.

Clinical Cancer Research 2008;1239 14(4) February 15, 2008.

 

September 2007
Toxicological Assessment of a Particulate Yeast (1,3)-ß-D-Glucan in Rats.
Food and Chemical Toxicology. (2007), doi:10.1016/j.fct.2007.03.013.


August 2007
Combined Yeast ß-Glucan and Antitumor Monoclonal Antibody Therapy Requires C5a-Mediated Neutrophil Chemotaxis via Regulation of Decay-Accelerating Factor CD55.

Cancer Research. 2007 67: 7421-7430.

 

December 2006

β-Glucan is a Fungal Determinant for Adhesion-Dependent Human Neutrophil Functions.

Journal of Immunology. Dec 2006; 177: 8667 - 8675.

 

August 2006
Yeast β-Glucan Amplifies Phagocyte Killing of iC3b-opsonized Tumor Cells via CR3-Syk-PI3-kinase Pathway
The Journal of Immunology. 2006 Aug 1;177(3):1661-9

 

April 2006
The Effect of PGG-Beta-Glucan on Neutrophil Chemotaxis in Vivo
Journal of Leukocyte Biology. 2006 Apr; 79 (4:667-75). Epub 2006 Jan 13.

 

January 2006
Beta-Glucan Enhances Complemented-Mediated Hematopoietic Recovery after Bone Marrow Injury
Blood. 15 January 2006. Volume 107, Number 2

 

June 2005
C5a-Mediated Leukotriene B4-Amplified Neutrophil Chemotaxis is Essential in Tumor Immunotherapy Facilitated by Anti-Tumor Monoclonal Antibody and ß-Glucan
The Journal of Immunology. 2005 174:7050-7056

 

May 2005
Yeast Whole Glucan Particle ß-Glucan in Conjunction with Anti-tumour Monoclonal Antibodies to Treat Cancer
Expert Opinion on Biological Therapy. May 2005, Vol. 5, No. 5, Pages 691-702

 

September 2004
ß-Glucan Affects Leukocyte Navigation in a Complex Chemotactic Gradient
Surgery. 2004: 136:384-89

 

July 2004
Mechanism by Which Orally Administered ß-1,3-Glucans Enhance the Tumorcidial Activity of AntiTumor Monoclonal Antibodies in Murine Tumor Models
The Journal of Immunology. 2004: 173: 797-806

 

March 2004
Complement Function in Monoclonal Antibody-Mediated Cancer Immunotherapy
Review published in Trends in Immunology.

 

December 2003
ß-Glucan Functions as an Adjuvant for Monoclonal Antibody Immunotherapy by Recruiting Tumoricidal Granulocytes as Killer Cells
Cancer Research. 63, 9023-9031, Dec. 15, 2003

 

March 2003
Anthrax-Protective Effects of Yeast Beta 1,3 Glucans
Medscape General Medicine.

 

May 2002
Pilot Study: Orally-Administered Yeast ß1,3-glucan Prophylactically Protects Against Anthrax Infection and Cancer in Mice
The Journal of the American Nutraceutical Association.
Vol. 5, No. 2, Spring 2002


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